■ Students involved

Rodrigo Hernandez (rohemi_14@hotmail.com)

SeokJin Kim (kimsj5522@snu.ac.kr)

■ Description
  Raman spectroscopy is a nonionizing, label-free, non-destructive optical vibration spectroscopic method whichallows for molecular characterization of samples (biological or non-biological). It relies on the inelastic scatteringof light from different biomolecules. This technique has been previously used for the detection and diagnosis of different types of cancer. Raman spectroscopy can effectively be employed to evaluate radiation inducedmolecular changes of biological samples.It can be a very powerful technique to evaluate the molecularfingerprint of cancer cells and provide an additional support for radiotherapy plans.Our goal is to characterize thebiochemical response of different cancer cell-lines to different raditation particles commonly used inradiatiotherapy and classify their intrinsic radiosensitivity based on Raman Spectroscopy. In addition, we aim tosupport to elucidate the intracellular biochemical processes behind the MNP radioenhancement.