■ Students involved

  Kiok Han (todo)

  Rodrigo Hernandez (rohemi_14@hotmail.com)

  SeokJin Kim (kimsj5522@snu.ac.kr)

  Raman spectroscopy is a nonionizing, label-free, non-destructive optical vibration spectroscopic method which allows for molecular characterization of samples (biological or non-biological). It relies on the inelastic scattering of light from different biomolecules. This technique has been previously used for the detection and diagnosis of different types of cancer. Raman spectroscopy can effectively be employed to evaluate radiation induced molecular changes of biological samples.It can be a very powerful technique to evaluate the molecular fingerprint of cancer cells and provide an additional support for radiotherapy plans.Our goal is to characterize the biochemical response of different cancer cell-lines to different raditation particles commonly used in radiatiotherapy and classify their intrinsic radiosensitivity based on Raman Spectroscopy. In addition, we aim to support to elucidate the intracellular biochemical processes behind the MNP radioenhancement.