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EPR

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■ Students involved

  Kwon Choi (kwon.choi84@gmail.com) 

  Jong In Park (jipark815@gmail.com)

 

 

■ Description

   When emergency accident occurs related with radiation and nuclear power, workers have personal dosimeter on their body. However, people who live near the region of radiation emergency have no personal dosimeter.

   Dicentric analysis, translocation analysis, PCC analysis, and MN analysis are widely used biological method to quantify DNA aberration caused by irradiated dose from accidents. However, Analysis of sample generally takes 

several days.

Electron paramagnetic resonance spectroscopy is a method for studying materials with unpaired electrons. The basic concepts of EPR are analogous to those of nuclear magnetic resonance, but it is electron spins that are excited instead of the spins of atomic nuclei. EPR spectroscopy is only method to measure free-radicals directly.

   There are few EPR spectrometers for dosimetry in radiation safety institution. EPR spectroscopy can measure irradiated dose within 1 hour from sample. But, the most devices use extracted tooth or in-vitro samples in South Korea. Therefore, we are developing the EPR spectrometer for tooth dosimetry since 2015 funded by Nuclear Safety and Security Commission (NSSC). Our groups have focused on tooth dosimetry with principle of EPR spectroscopy. We aim to complete construction of EPR spectroscopy and establishment of dose-response curve until 2018 with following goals (1) Sensitivity < 1 Gy (2) processing rate 10-20 persons/hour (3) transportable device

 

   Prof. Hiroshi Hirata is the adviser who is leading scientist of international EPR society and MRI group of Hokkaido University. RPLab and Prof. Hiroshi Hirata have a close cooperation with each other. Prof. Harold M. Swartz (Dartmouth EPR center) is leading scientist and pioneer in EPR spectroscopy and biomedical application. Prof. Harold M. Swartz and his group is also our honorable close collaborator.